Diode Array Spectrometers

Augment Fluorescence-Based Research

Dr. Thomas Rasmussen

Read the contributed article from the March/April 2021 issue of BioPhotonics about Diode Array Spectrometers, written by Dr. Thomas Rasmussen.

Fluorescence spectroscopy is a key technology for very sensitive measurements of low concentration biological material. Currently, the technology is of high interest because fluorometers can be used to detect COVID-19.

Traditional fluorometers are built with a single application in mind using optical filters and photodiodes. Such instruments typically detect emission at 1-2 wavelengths only. However, there is a trend in the market to build more versatile instruments that can detect multiple fluorophores and multiple wavelengths. At the same time, the miniaturization of diode array spectrometers has enabled high-performance spectral sensors that can outperform optical filters in both cost and complexity when the number of required filters rises above 3-4.

In this article, we review the recent development in the miniaturization of diode array sensors for fluorescence and highlight some of the new opportunities enabled by these sensors.